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The same principles operate for structured proteins that bind to membrane surfaces. Coli metabolism, 251 flux vector, 89 flux-balance analysis, 197 Fourier analysis, 189 functional states, 16 choosing, 21 constraints on, 19 fundamental subspaces, 90, 118 choice of basis, 119 contents of, 119 dimensions of, 91, 118 orthonormal bases for, 122 futile cycle, 148, 156 GAL regulon, 65 galactose, 56 gap analysis, 34, 44, 190 gene expression constitutive, 60 gene therapy, 4 gene-protein-reaction associations, 40 generalist phenotype, 189 genetic circuits, 3 definition of, 3 properties, 3 properties of, 4 genetic code, 193 genetic perturbation, 63 genetic programs, 179 genome annotation, 35 topological organization, 61 genome-scale Ojline reconstruction, 265 metabolism, 34 Genomes On-Line Database, 37 genomic taxonomy, 4 genomics, 1 genotypephenotype relationship, 4 Geobacter sulfurreducens, 44 Gibbs free energy, 99 glucose, 55 glucose-6-phosphate dehydrogenase, 235 GPR associations, 260 heat shock, 192 Helicobacter pylori reconciliation of metabolic reaction, 43 hierarchical organization, 182, 284, 285 decomposition of, 4 in biological systems, 189 in biology, 22 in metabolic networks, 30 in organisms, 189 in regulatory networks, 60 in signaling networks, 79 in systems biology, 7 physics versus biology.

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