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Lear, aetiology, and pathogenesis Clinical assessment Treatment Epidemiology Aetiology Pathogenesis Pathophysiology Cardiac Non-cardiac Cause of non-cardiac pathophysiology in heart failure Symptoms Clinical examination Investigations Diuretics Digoxin Direct-acting vasodilators Angiotensin-converting enzyme (ACE) inhibitors b-Blockers Antiarrhythmic agents Oral, positive inotropic agents Anticoagulants and antiplatelet agents Angiotensin-II receptor antagonists Non-pharmacological treatments Patient education Specialist heart failure clinics and outreach nursing services Rest and exercise Other treatments Prognosis Prognostic factors and markers Specific prognostic indicators Further reading Introduction Heart failure is a common condition, carrying a high burden of disability and mortality.

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